Fig. 6.

Effects of administration of adenovirus encoding kinase-inactive PKC-ζ (KI-ζ) on fasting serum levels of triglycerides, free fatty acids (FFA), total cholesterol, and glucose; and hepatic levels of triglycerides, ACC mRNA, IL-1β mRNA, and TNFα mRNA in high-fat–fed mice (A) and heterozygous muscle-specific PKC-λ knockout (Mλ-Het-KO) mice (B). WT = wild-type mice. Vec = adenovirus vector. Rel U = relative units. Values are mean ± SEM of (N) determinations and P values (as per ANOVA) depict comparisons of indicated groups.