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. Author manuscript; available in PMC: 2010 Apr 15.
Published in final edited form as: Cancer Res. 2009 Apr 7;69(8):3589–3596. doi: 10.1158/0008-5472.CAN-08-4016

Table 1. H2O2 sensitivity in breast cell lines.

Breast cell lines of various subtypes as indicated were analyzed for H2O2 sensitivity by MTT assay. The average IC50 values determined from the dose-response curve of at least three independent experiments are shown as an average ± s.e.m. p-value was determined by student t-test relative to the normal-like cell lines

Cell Line H2O2 IC50 (μM) p-Value

Normal-like
MCF10A 1008 ± 14
MCF12A 700 ± 265
Luminal 0.0981
MCF7 550 ± 58
BT474 750 ± 129
T47D 500 ± 100
MDAMB361 483 ± 126

BRCA1 0.0094**
SUM149PT 95 ± 30
SUM1315MO2 192 ± 63
HCC1937 23 ± 12
MDAMB436 367 ± 58

Basal-like 0.0003**
BT549 13 ± 6
hs578T 150 ± 87
MDAMB231 333 ± 76
HCC38 20 ± 5
HCC1143 20 ± 10
HCC1806 50 ± 29
HCC1500 38 ± 37
MDAMB468 333 ± 58
**

p<0.01.