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. Author manuscript; available in PMC: 2010 Jul 10.
Published in final edited form as: Toxicol Lett. 2009 Mar 20;188(1):38–44. doi: 10.1016/j.toxlet.2009.03.005

Fig 1. CAR activators protect the liver against bile acid-induced toxicity.

Fig 1

(A) A mid-section of the left liver lobe was evaluated and pictures are representative of treatment group pathology. Multifocal hepatic necrosis (arrows) is easily distinguished from surrounding parenchyma. 50× magnification. (B) Serum ALT values with results presented as mean concentration ± S.E.M. * Indicates p ≤ 0.05 compared to respective CO; † indicates p ≤ 0.05 compared to respective LCA-only.