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. Author manuscript; available in PMC: 2010 Jul 10.
Published in final edited form as: Toxicol Lett. 2009 Mar 20;188(1):38–44. doi: 10.1016/j.toxlet.2009.03.005

Fig. 3. Apoptosis-related expression in liver.

Fig. 3

(A) mRNA expression of anti-apoptotic Mcl-1 and Bcl-xL, pro-apoptotic expression of Bak and Bax as quantified by the bDNA signal amplification assay. N= 4–6 per group, except for WT PCN, N=3. Data are expressed as relative light units (RLU) ± S.E.M. * Indicates p ≤ 0.05 compared to respective CO; † indicates p ≤ 0.05 compared to respective LCA-only. (B) Cytosolic fractions were isolated and analyzed by Western blotting for protein expression of hepatic Mcl-1, Bcl-xL, Bak and Bax, as well as PARP. Two animals per treatment group are shown.