. 2009 Apr 27;7:17. doi: 10.1186/1741-7007-7-17

Table 1.

Regulation of PTH gene expression in HEK293 cells transfected with the CaR and hPTH plasmids and in the rat parathyroid by calcium

	HEK293 cells + CaR	Rat parathyroid
PTH transcription	not applicable	no effect

PTH mRNA levels	regulated	regulated

PTH mRNA stability	regulated	regulated

PTH secretion	unknown	regulated

AUF1 and KSRP-PTH mRNA interactions	regulated	regulated

AUF1 protein modifications	regulated	regulated

regulation by [Ca²⁺]_oand R568	regulated	regulated

AUF1 = AU rich binding factor; KSRP = KH domain splicing regulatory protein; PTH = parathyroid hormone