Table 2.

Numerical density (N_V) of cells in frontal, parietal, cingulate, and retrosplenial cortex; mediodorsal, laterodorsal, and ventral thalamus; caudate; and subiculum in rats subjected to traumatic head injury at the age of 7 days

Position	Sham			Trauma
	Normal cells, NV normal	Degenerating cells, NV spontaneous	%	Degenerating cells, NV ipsilateral	%	Degenerating cells, NV contralateral	%
Frontal cortex II	0.1897  ±  0.0045	0.0032  ±  0.0003	1.67	0.0198  ±  0.0038*	10.45	0.0101  ±  0.0021*	5.35
Frontal cortex IV	0.1212  ±  0.0103	0.0002  ±  0.00003	0.16	0.0051  ±  0.0010†	4.20	0.0045  ±  0.0010†	3.74
Parietal cortex II	0.2239  ±  0.0134	0.0022  ±  0.0006	0.96	0.0689  ±  0.0081‡	30.77	0.0137  ±  0.0019*	6.12
Parietal cortex IV	0.1360  ±  0.0063	0.0003  ±  0.00008	0.26	0.0852  ±  0.0017†	6.26	0.0009  ±  0.0002*	0.69
Cingulate II	0.1958  ±  0.0113	0.0030  ±  0.0004	1.54	0.0515  ±  0.0088†	26.32	0.0091  ±  0.0017*	4.67
Cingulate IV	0.1281  ±  0.0061	0.0002  ±  0.00003	0.13	0.0098  ±  0.0011‡	7.62	0.0012  ±  0.0003*	0.91
Retrosplenial II	0.2159  ±  0.0139	0.0016  ±  0.0003	0.74	0.0538  ±  0.0080‡	24.93	0.0026  ±  0.0003*	1.21
Retrosplenial IV	0.1230  ±  0.0109	0.0004  ±  0.00007	0.33	0.0415  ±  0.0057‡	33.71	0.0008  ±  0.0001*	0.67
Caudate	0.2225  ±  0.0111	0.0006  ±  0.0001	0.29	0.0048  ±  0.00009†	2.16	0.0029  ±  0.0061*	1.31
Mediodorsal thalamus	0.1683  ±  0.0064	0.0002  ±  0.00004	0.14	0.0015  ±  0.00003‡	0.88	0.0010  ±  0.0002*	0.59
Laterodorsal thalamus	0.1339  ±  0.0131	0.0004  ±  0.00006	0.30	0.0307  ±  0.0072‡	22.95	0.0020  ±  0.0005*	1.53
Ventral thalamus	0.1129  ±  0.0026	0.0001  ±  0.00003	0.11	0.0023  ±  0.0005†	2.04	0.0014  ±  0.0004*	1.22
Subiculum	0.1681  ±  0.0082	0.0004  ±  0.00006	0.22	0.0520  ±  0.0063‡	30.93	0.0033  ±  0.0006†	1.99

Assessment of cell densities were performed 24 hr after head trauma or sham surgery in DeOlmos cupric silver or methylene blue/azure II-stained sections of the whole brain. N_V values of normal and silver-accumulating cells were determined by using the unbiased disector technique and are shown as means ± SEMs × 10⁶ cells per mm³ in 6–16 rats. II and IV stand for cortical layers II and IV. *, P < 0.05;  

^†, P < 0.01;  

^‡, P < 0.001; Student’s t test.