TABLE 7.

Effectof inhibitors of fatty acid biosynthesis and analogues on growth and TSST-1production by S. aureus

S. aureus strain and compound	Compound concn (μg/ml)	% Control
		Growth	TSST-1
MN8
4-Hydroxydiphenylmethane	2.00	37.1	77.2
	1.00	70.2	91.0
Cerulenin	120.00	50.0	10.7
	80.00	235.1	8.4
Hexachlorophene	2.00	123.7	19.6
	1.00	143.81	48.1
Triclosan	0.05	0.0	NDa
	0.01	5.6	ND
FRI-1187
Hexachlorophene	3.00	35.2	63.5
	1.50	75.0	74.3
Triclosan	0.50	35.5	3.7
	0.05	136.4	9.9

^aND, not determined.