TABLE 1.

Antimicrobial activities of ultrashort cationic lipopeptides^a

Control organism	MIC (μg/ml)
	Gentamicin	αC16-KGGK	αC16-KKKK	αC16-KAAK	αC12-KLLK	αC16-KGGK	αC16-KKKK	αC16-KAAK	αC12-KLLK	βC16-KGGK	βC16-KKKK	βC16-KAAK	βC12-KLLK
S. aureus ATCC 29213	1	8	32	16	16	16	16	8	16	16	16	64	32
MRSA ATCC 33592	2	16	16	16	16	16	16	32	16	32	16	32	32
S. epidermidis ATCC 14990	0.25	4	4	8	16	8	4	4	8	8	4	8	16
MRSE CAN-ICU 61589	32	8	8	8	16	8	8	8	16	16	4	16	32
E. faecalis ATCC 29212	ND	8	16	16	32	16	32	16	32	32	32	32	64
E. faecium ATCC 27270	ND	16	16	8	16	16	16	8	32	32	16	32	32
S. pneumoniae ATCC 49619	4	128	>64	128	128	128	>32	128	64	128	128	>64	128
E. coli ATCC 25922	1	16	16	16	128	16	32	32	64	32	16	64	64
E. coli CAN-ICU 61714	128	16	16	16	128	64	32	32	64	32	32	64	64
E. coli CAN-ICU 63074	8	16	32	16	128	16	32	32	64	32	32	64	64
P. aeruginosa ATCC 27853	8	64	64	32	128	64	32	64	128	64	64	256	128
P. aeruginosa CAN-ICU 62308	128	64	256	64	128	64	256	64	128	>64	128	128	128
S. maltophilia CAN-ICU 62584	>512	128	256	128	>256	64	256	128	>256	256	256	>128	256
A. baumannii CAN-ICU 63169	128	128	256	128	>64	64	256	128	>256	128	256	256	>128
K. pneumoniae ATCC 13883	0.25	64	256	128	256	64	256	128	>64	128	128	>128	256

^aUnderlined letters represent the positions of the d-enantiomers. MRSA, methicillin-resistant S. aureus; ND, not determined.