TABLE 2.

Pfdhfr genotypes and microsatellite markers from isolates collected in 1999 and 2006 to 2007

Yr of collection (no. of isolates)	No. of samples froma:			Pfdhfr genotypeb					Microsatellite haplotype at the following locusc:					Haplogroup	Frequency
	CC	PC	Iquitos	BR	C50R	N51I	S108N	I164L	−5.30	−3.87	−0.3	0.52	5.87
1999 (104)	25	28		Yes	C	I	N	L	223	216	101	97	122	DHFR-A1	0.51
	1	0	Yes	C	I	N	L	223	220	101	97	122	DHFR-A2	0.01
	0	31	No	C	N	N	I	223	195	125	97	108	DHFR-B1	0.30
	14	5	No	C	N	N	I	202	209	97	103	108	DHFR-C1	0.18
2006-2007 (62)			8	Yes	C	I	N	L	223	216	101	97	122	DHFR-A1	0.13
	1	Yes	C	I	N	L	223	216	101	97	120	DHFR-A3	0.016
	1	Yes	C	I	N	L	225	216	101	97	122	DHFR-A4	0.016
	3	Yes	R	I	N	I	202	209	97	99	120	DHFR-D1	0.05
	44	No	C	N	N	I	223	195	125	97	108	DHFR-B1	0.71
	1	No	C	N	N	I	223	195	113	97	108	DHFR-B2	0.016
	4	No	C	N	N	I	202	209	97	103	108	DHFR-C1	0.065

^aCC, Caballococha; PC, Padre Cocha.

^bMutations are indicated by boldface.

^cMicrosatellite loci are named according to their positions (in kilobases) from the gene; negative positions are 5′ and positive positions are 3′ to the gene.