TABLE 5.

Pfmdr-1 genotypes and microsatellite markers from isolates collected in 1999 and 2006 to 2007

Yr of collection (no. of isolates)	No. of samples froma:			Pfmdr-1 genotypeb						Microsatellite haplotype at the following locusc:						Haplogroup	Frequency
	CC	PC	Iquitos	N86Y	D142G	Y184F	S1034C	N1042D	D1246Y	−4.2	−3.4	−1.2	id	0.56	3.8
1999 (104)	1			N	D	F	S	D	D	204	127	197	206	192	169	MDR-A1	0.01
	4	N	G	F	S	D	D	196	133	203	206	178	189	MDR-B1	0.038
	4	N	G	F	S	D	D	196	135	203	206	178	189	MDR-B2	0.038
	4	N	G	F	S	D	D	196	127	203	206	178	189	MDR-B3	0.038
	26	N	D	F	C	D	D	204	127	197	206	192	169	MDR-A1	0.25
	1	N	D	F	C	D	D	204	127	200	206	192	169	MDR-A2	0.01
	2	N	D	F	C	D	D	204	133	197	206	192	169	MDR-A3	0.02
	1	N	D	F	C	D	D	204	133	200	206	192	169	MDR-A4	0.01
	1	N	D	F	C	D	D	204	119	197	206	192	169	MDR-A5	0.01
	1	N	D	F	C	D	D	204	121	197	206	192	169	MDR-A6	0.01
	4	N	D	F	C	D	D	196	133	203	206	178	189	MDR-B1	0.038
	1	N	D	F	C	D	D	196	135	203	206	178	189	MDR-B2	0.01
	7	N	D	F	C	D	D	196	127	203	206	178	189	MDR-B3	0.067
	1	N	D	F	C	D	D	196	133	197	206	178	189	MDR-B4	0.01
	1	N	D	F	C	D	D	196	127	203	206	178	169	MDR-B5	0.01
	19	14	N	D	F	C	D	Y	204	127	197	206	192	169	MDR-A1	0.32
	4	3	N	D	F	C	D	Y	204	133	197	206	192	169	MDR-A3	0.067
	2	N	D	F	C	D	Y	204	127	197	206	192	189	MDR-A7	0.02
	1	N	D	F	C	D	Y	196	133	203	206	178	189	MDR-B1	0.01
	1	N	D	F	C	D	Y	196	127	203	206	178	169	MDR-B5	0.01
	1	N	G	F	C	D	D	196	127	203	206	178	189	MDR-B3	0.01
2006-2007 (62)			1	N	D	F	S	D	D	196	133	203	206	178	189	MDR-B1	0.016
	10	N	G	F	S	D	D	196	133	203	206	178	189	MDR-B1	0.16
	1	N	G	F	S	D	D	196	135	203	206	178	189	MDR-B2	0.016
	1	N	G	F	S	D	D	196	133	203	206	111	189	MDR-B6	0.016
	1	N	G	F	S	D	D	204	133	203	206	178	189	MDR-B7	0.016
	1	N	G	F	S	D	D	196	133	203	206	194	189	MDR-B8	0.016
	1	N	G	F	S	D	D	204	133	203	206	194	189	MDR-B9	0.016
	3	N	G	F	S	D	D	196	133	205	206	178	189	MDR-B10	0.05
	25	N	D	F	C	D	D	204	127	197	206	192	169	MDR-A1	0.40
	2	N	D	F	C	D	D	204	127	200	206	192	169	MDR-A2	0.03
	1	N	D	F	C	D	D	204	127	197	206	194	169	MDR-A8	0.016
	3	N	D	F	C	D	D	196	133	203	206	178	189	MDR-B1	0.05
	1	N	D	F	C	D	D	196	135	203	206	178	189	MDR-B2	0.016
	6	N	D	F	C	D	Y	204	127	197	206	192	169	MDR-A1	0.1
	1	N	D	F	C	D	Y	204	127	200	206	192	169	MDR-A2	0.016
	1	N	D	F	C	D	Y	204	127	197	206	194	169	MDR-A8	0.016
	1	N	D	F	C	D	Y	196	127	197	206	192	169	MDR-A9	0.016
	1	N	G	F	C	D	D	196	133	203	206	178	189	MDR-B1	0.016
	1	N	G	F	C	D	D	196	127	205	206	178	169	MDR-C1	0.016

^aCC, Caballococha; PC, Padre Cocha.

^bBoldface letters indicate mutations.

^cMicrosatellite loci are named according to their positions (in kilobases) in relation to the gene; negative positions are 5′ and positive positions are 3′ to the gene.

^dLocus within Pfmdr-1.