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Distributions of S. pneumoniae PspA gene copy numbers in sputum among ODK0501- and culture-positive and -negative populations. Vertical axis, copy number of the PspA gene calculated from real-time PCR. •, S. pneumoniae culture negative; ○, S. pneumoniae culture positive. ODK0501-positive and culture-positive populations contain more copies of the S. pneumoniae PspA gene. Copy numbers significantly differed between ODK0501-positive and -negative populations (P < 0.001).
