TABLE 3.
GO terms of the ontology biological process that are significantly overrepresented by Cdc53p depletion
| Cluster | GO term description | Pa | No. of regulated genesb | Background frequencyc |
|---|---|---|---|---|
| I | Sulfur metabolic process | 1.32E−09 | 18 | 48 |
| Nitrogen compound metabolic process | 7.41E−09 | 42 | 226 | |
| Amino acid and derivative metabolic process | 7.94E−09 | 36 | 178 | |
| Organic acid metabolic process | 3.54E−08 | 47 | 278 | |
| II | Transport | 0.3 | 54 | 687 |
| Ion transport | 1.09E−05 | 19 | 90 | |
| Lipid transport | 4.56E−04 | 6 | 16 | |
| Oligopeptide transport | 7.94E−04 | 5 | 12 | |
| Vitamin transport | 1.21E−03 | 3 | 4 | |
| Basic amino acid transport | 9.08E−03 | 3 | 7 | |
| III | Response to stimulus | 0.31 | 33 | 409 |
| Response to temp stimulus | 3.52E−04 | 7 | 21 | |
| Response to oxidative stress | 5.90E−04 | 11 | 51 | |
| IV | Respiratory chain complex IV assembly | 1.23E−03 | 4 | 8 |
| V | Ethanol metabolic process | 2.09E−03 | 4 | 9 |
| VI | Cell separation during cytokinesis | 3.47E−03 | 5 | 16 |
| VII | Fermentation | 3.47E−03 | 5 | 16 |
| VIII | Chromatin assembly or disassembly | 3.91E−03 | 10 | 55 |
a
That is, the significance of overrepresentation of listed GO terms comparing the transcriptional profiles of strains KTY31 to KTY3 in the presence of doxycycline.
b
That is, the number of differentially regulated genes belonging to the listed GO terms.
c
That is, the number of genes belonging to listed GO terms on a genome-wide level.