TABLE 5.
Subclassification of the GO term transport of the transcriptional profile of Cdc53p-depleted cells
| GO term | Pa | No. of regulated genesb | Background frequencyc | Regulation of KTY31 vs KTY3 | Gene name (open reading frame no.) |
|---|---|---|---|---|---|
| Transport | 0.3 | 54 | 687 | ||
| Ion transport | 1.09E-05 | 19 | 90 | ||
| Metal ion transport | 1.08E-04 | 11 | 57 | Up | CFL2 (orf19.1264), CTR1 (orf19.3646), FTR1 (orf19.7219), CRP1 (orf19.4784), orf19.2006.1, FET3 (orf19.4211), FET34 (orf19.1206), COX19 (orf19.4967), CFL5 (orf19.1930), FTR2 (orf19.7231), ATX1 (orf19.2369.1) |
| 2 | Down | orf19.4940, ENA21 (orf19.5170) | |||
| Other | 4 | Up | PHO87 (orf19.2454), SSU1 (orf19.7313), SUL2 (orf19.2738), MEP1 (orf19.1614) | ||
| 2 | Down | orf19.2959.1, PHO84 (orf19.1172) | |||
| Lipid transport | 4.56E-04 | 1 | 16 | Up | orf19.4342 |
| 5 | Down | RTA2 (orf19.24), GIT2 (orf19.1978), RTA3 (orf19.23), GIT1 (orf19.1979), orf19.34 | |||
| Oligopeptide transport | 7.94E-04 | 5 | 12 | Down | OPT4 (orf19.176), PTR2 (orf19.6937), IFC3 (orf19.3749), OPT9 (orf19.2584), OPT1 (orf19.2602) |
| Vitamin transport | 1.21E-03 | 1 | 4 | Up | TNA1 (orf19.4335) |
| 2 | Down | PHO113 (orf19.2619), PHO112 (orf19.3727) | |||
| Basic amino acid transport | 9.08E-03 | 1 | 7 | Up | CAN2 (orf19.111) |
| 2 | Down | ALP1 (orf19.2337), orf19.4940 |
a
That is, the significance of overrepresentation of the listed GO terms comparing the transcriptional profiles of strains KTY31 to KTY3 in the presence of doxycycline.
b
That is, the number of differentially regulated genes belonging to the listed GO terms.
c
That is, the number of genes belonging to the listed GO terms on a genome-wide level.