TABLE 6.
Subclassification of the GO term filamentous growth of the transcriptional profile of Cdc53p-depleted cells
| GO term | Pa | No. of regulated genesb | Background frequencyc | Regulation of KTY31 vs KTY3 | Gene name (open reading frame no.) |
|---|---|---|---|---|---|
| Filamentous growth | 0.82 | 23 | 323 | ||
| Invasive growth (sensu Saccharomyces) | 0.08 | 1 | 15 | Up | ALS4 (orf19.4555) |
| 2 | Down | CDC14 (orf19.4192), GAL10 (orf19.3672) | |||
| Pseudohyphal growth | 0.10 | 2 | 36 | Up | STE11 (orf19.844), ALS4 (orf19.4555) |
| 3 | Down | FKH2 (orf19.5389), ASH1 (orf19.5343), CPH2 (orf19.1187) | |||
| Signal transduction during filamentous growth | 0.43 | 1 | 8 | Down | CDC5 (orf19.6010) |
| Hyphal growth | 0.73 | 3 | 139 | Up | ALS2 (orf19.1097), UTR2 (orf19.1671), ALS4 (orf19.4555) |
| 5 | Down | FKH2 (orf19.5389), MCM1 (orf19.7025), CDC14 (orf19.4192), CPH2 (orf19.1187), SSK1 (orf19.5031) | |||
| Other | 4 | Up | SSU1 (orf19.7313), PHHB (orf19.2079), FGR3 (orf19.3845), FGR43 (orf19.4786) | ||
| 7 | Down | CLB4 (orf19.7186), CZF1 (orf19.3127), orf19.6720, ECM4 (orf19.2613), GAT2 (orf19.4056), CHA1 (orf19.1996), FGR41 (orf19.4910) |
a
That is, the significance of overrepresentation of listed GO terms comparing the transcriptional profiles of strains KTY31 to KTY3 in the presence of doxycycline.
b
That is, the number of differentially regulated genes belonging to the listed GO terms.
c
That is, the number of genes belonging to the listed GO terms on a genome-wide level.