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. 2009 Mar 20;75(10):3137–3145. doi: 10.1128/AEM.02667-08

FIG. 1.

FIG. 1.

Schematic representation of (S)-3HB or (R)-3HB synthesis from glucose in engineered E. coli. BktB, acetoacetyl-CoA thiolase from R. eutropha H16; Thl, acetoacetyl-CoA thiolase from C. acetobutylicum ATCC 824; PhaA, acetoacetyl-CoA thiolase from R. eutropha H16; Hbd, (S)-3HB-CoA dehydrogenase from C. acetobutylicum ATCC 824; PhaB, (R)-3HB-CoA dehydrogenase from R. eutropha H16; Ptb, phosphotransbutyrylase from C. acetobutylicum ATCC 824; Buk, butyrate kinase from C. acetobutylicum ATCC 824; TesB, acyl-CoA thioesterase II from E. coli MG1655.