TABLE 1.
Content of variable genes in H. pylori isolates from patients with gastroduodenal diseases, defined using microarrays
| Group and patient | Age (yr) | Gender | No. of single isolates studieda | No. of variable genes per single isolate in patients with mixed infectiond | No. of variable genes per patiente |
|---|---|---|---|---|---|
| NAG patients | |||||
| 357b | 33 | F | 2 | A = 143; B = 112 | 152 |
| 284b | 41 | F | 2 | A = 93; B = 92 | 143 |
| 320b | 43 | F | 2 | A = 52; B = 131 | 138 |
| 103b | 37 | F | 2 | A = 81; B = 1 | 82 |
| 386c | 40 | M | 3 | A = 76; B = 72; C = 4 | 139 |
| 110 | 48 | M | 1 | 21 | |
| 370 | 44 | F | 1 | 187 | |
| 176 | 44 | M | 1 | 88 | |
| 345 | 35 | F | 1 | 85 | |
| 221 | 44 | F | 1 | 98 | |
| DU patients | |||||
| 174b | 41 | F | 2 | A = 31; B = 150 | 164 |
| 204b | 61 | M | 2 | A = 67; B = 113 | 126 |
| 372b | 46 | M | 2 | A = 43; B = 126 | 127 |
| 387b | 31 | M | 2 | A = 175; B = 127 | 181 |
| 355 | 46 | F | 1 | 30 | |
| 362 | 28 | F | 1 | 126 | |
| 263 | 55 | F | 1 | 3 | |
| 336 | 77 | F | 1 | 85 | |
| 261 | 52 | F | 1 | 100 | |
| 379 | 48 | F | 1 | 1 | |
| GC patients | |||||
| 510c | 44 | M | 4 | A = 25; B = 45; C = 13; D = 93 | 104 |
| 188 | 46 | F | 1 | 27 | |
| 206 | 61 | F | 1 | 88 | |
| 377 | 66 | M | 1 | 96 | |
| 401 | 60 | F | 1 | 30 | |
| 535 | 44 | F | 1 | 137 | |
| 456 | 57 | M | 1 | 124 | |
| 331 | 36 | F | 1 | 113 | |
| 443 | 69 | F | 1 | 77 |
a
Defined using RAPD fingerprinting.
b
Patients with two RAPD patterns.
c
Patients with more than two RAPD patterns.
d
Number of variable genes in each isolate. Each letter (A, B, C, or D) represents a single isolate with a different RAPD pattern.
e
Overall number of variable genes per patient, considering that in the case of mixed infection a gene was present when it was found in at least one of the isolates from this patient.