. 2009 Feb 23;77(5):2201–2211. doi: 10.1128/IAI.01284-08

TABLE 5.

H. pylori genes significantly more frequent in isolates from one disease group than in isolates from the other two gastroduodenal disease groups

Disease group and genes^a	Description and/or function(s) (reference)	Localization	P value^b
NAG
N/A, HP1499, JHP1392	Regulation of response to pH (8)	Outside PZs	0.0332
N/A, N/A, JHP0934		PZ2	0.0902
GC
N/A, N/A, JHP0616		Outside PZs	0.0412
N/A, N/A, JHP0927		PZ2	0.0593
N/A, N/A, JHP0960	Homology with a gene in plasmids of Campylobacter sp. (5)	PZ1	0.0685
N/A, N/A, JHP0961	Homology with a gene in plasmids of Campylobacter sp. (5)	PZ1	0.0767
cag7, orf13 and orf14, HP0527, JHP0476	cag pathogenicity island protein, DNA transfer protein (Agrobacterium VirB10 homolog)/cellular processes	cag PAI	0.0995
cag10, orf17, HP0530, JHP0479	cag pathogenicity island protein/cellular processes	PZ2	0.0995
cag23, cagE, HP0544, JHP0492	cag pathogenicity island protein/cellular processes	PZ2	0.0995
DU
N/A, N/A, JHP0951	Integrase/recombinase (xercd family)/modulation of the response to low pH and iron limitation (16)	PZ2	0.0374
N/A, N/A, JHP0950		PZ2	0.0744
N/A, HP1405, N/A	Modulation of the response to low pH (8, 30)	Outside PZs	0.0796
N/A, HP1381, N/A		Outside PZs	0.0859

Designation according to gene name, J99 genome sequence (1), and 26695 sequence (51).

The P value was obtained with the χ² test, comparing one disease group (i.e., NAG) with the other two groups (i.e., DU and GC).