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. 2009 Feb 23;77(5):1981–1991. doi: 10.1128/IAI.01382-08

FIG. 4.

FIG. 4.

High extracellular potassium levels inhibit Asc-dependent caspase-1 activation. An immunoblot of the p10 fragment of caspase-1 from combined supernatants and pellets of BMMs from wild-type (WT), Asc−/−, or Ipaf−/− mice is shown. Cells were infected for 4 h with wild-type, dotA, or flaA L. pneumophila at an MOI of 10 in the presence of an additional 50 mM NaCl or 50 mM KCl. Data are representative of three experiments.

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