TABLE 1.
Summary of the clinical characteristics of the 33 patients with HPIV4 infections
| Case | Mo | Sexa/age | Underlying disease(s)b | Diagnosisb | CXRd finding(s) | Genotype |
|---|---|---|---|---|---|---|
| 1 | April | M/1 yr | None | URTI, encephalopathy | Not done | HPIV4A |
| 2 | April | M/3 yr | None | Febrile convulsion | Not done | HPIV4A |
| 3 | April | M/5 mo | G6PD deficiency | URTI, febrile wheeze | Clear | HPIV4A |
| 4 | May | M/7 mo | None | GE | Clear | HPIV4A |
| 5 | May | M/1 yr | None | Febrile wheeze | Perihilar streakiness | HPIV4B |
| 6 | July | F/5 yr | None | Febrile illness, epilepsy | Left perihilar streakiness | HPIV4A |
| 7 | July | M/2 yr | None | URTI | Left perihilar, LLZ haziness | HPIV4A |
| 8 | July | M/5 yr | None | URTI, febrile convulsion | Not done | HPIV4B |
| 9 | July | M/6 yr | None | Pneumonia, asthma | Perihilar haziness | HPIV4B |
| 10 | July | M/18 yr | Brittle asthma | Asthma | Not done | HPIV4B |
| 11 | July | M/11 mo | Ex-prematurity, developmental delay, eczema | Pneumonia | Upper zone haziness | HPIV4B |
| 12 | August | F/94 yr | Old CVA, schizophrenia, glaucoma | Pneumonia | Lower zone haziness | HPIV4A |
| 13 | August | M/70 yr | Dementia, DM | Pneumonia | RLZ haziness | HPIV4A |
| 14 | August | F/72 yr | Dementia, DM, bronchiectasis, cholangitis | Pneumonia | RMZ and RLZ haziness | HPIV4A |
| 15 | September | M/2 yr | None | URTI | Clear | HPIV4B |
| 16c | November | F/2 yr | Epilepsy | URTI | Clear | HPIV4B |
| 17 | November | F/6 yr | None | Pneumonia | Perihilar haziness | HPIV4B |
| 18 | November | M/5 mo | None | URTI | Clear | HPIV4B |
| 19 | November | M/6 mo | Ex-prematurity, chronic lung disease, IVH | Febrile wheeze | Clear | HPIV4B |
| 20 | November | F/7 mo | Neuroblastoma | Tracheitis | Clear | HPIV4A |
| 21 | November | M/11 yr | Asthma | Pneumonia, asthma | RUL and RML collapse/ consolidation | HPIV4A |
| 22 | November | F/5 yr | None | URTI | Clear | HPIV4A |
| 23 | November | F/4 yr | None | Pneumonia, gastritis | RLZ haziness | HPIV4A |
| 24c | December | F/3 yr | None | Febrile wheeze, rotavirus GE | Not done | HPIV4A |
| 25 | December | F/1 mo | None | URTI | Clear | HPIV4B |
| 26 | January | M/1 yr | None | URTI, foreign body aspiration | Patchy opacities | HPIV4B |
| 27 | January | M/2 yr | Klinefelter syndrome | URTI, UTI | Clear | HPIV4B |
| 28 | January | M/6 yr | None | URTI, GE | Not done | HPIV4A |
| 29 | January | M/6 mo | None | URTI, rotavirus GE | Not done | HPIV4B |
| 30 | Feb | F/4 yr | Febrile convulsion | URTI | Left perihilar shadow | HPIV4A |
| 31 | Feb | M/7 yr | None | URTI, drug rash | Peribronchial and left hilar cuffing | HPIV4A |
| 32 | March | F/1 yr | Epilepsy | Febrile illness, status epilepticus | Clear | HPIV4A |
| 33 | March | F/5 yr | Asthma | Pneumonia, asthma | Perihilar haziness | HPIV4B |
| 34 | March | M/4 mo | Choroid plexus cyst, truncal hypotonia | URTI | Not done | HPIV4A |
a
M, male; F, female.
b
G6PD, glucose-6-phosphate dehydrogenase; CVA, cerebrovascular accident; DM, diabetes mellitus; IVH, intraventricular hemorrhage; URTI, upper respiratory tract infection; GE, gastroenteritis; UTI, urinary tract infection.
c
Cases with cell culture positive for HPIV4.
d
CXR, chest X-ray; LLZ, left lower zone; RLZ, right lower zone; RMZ, right middle zone; RUL, right upper lobe; RML, right middle lobe.