TABLE 2.
Index case sputum smear grading in relation to genotype, as well as number of child contacts infected and/or diseased, in relation to index case sputum smear grading
| Group | No. of cases with the following sputum smear gradinga:
|
||||
|---|---|---|---|---|---|
| Sm− | Sm1+ | Sm2+ | Sm3+ | Total | |
| Genotype | |||||
| Beijing | 4 | 24 | 12 | 17 | 57 |
| LAM | 6 | 14 | 2 | 5 | 27 |
| Haarlem | 0 | 3 | 4 | 3 | 10 |
| Xb | 5 | 10 | 2 | 6 | 23 |
| Otherc | 0 | 8 | 4 | 10 | 22 |
| Multipled | 0 | 6 | 4 | 8 | 18 |
| Total | 15 | 65 | 28 | 50 | 157 |
| Child contacts | |||||
| Uninfected | 17 | 33 | 18 | 33 | 101 |
| Infected | 2 | 49 | 23 | 44 | 118 |
| Diseasede | 0 | 16 | 6 | 12 | 34 |
| Total | 19 | 82 | 41 | 77 | 219 |
Smear grading reflects the highest grading recorded in any specimen collected from a particular individual or household. Sm−, smear negative; Sm1+ to Sm3+, smear-positive grades 1 to 3, respectively.
X, European clade of IS6110 low banders, as identified by spoligotyping.
Other, any genotype family with a frequency of less than 10 cases.
Multiple, households with multiple index cases or in which more than one genotype was identified in a single index case (mixed infection).
Children with probable active TB represent a subgroup of those infected.