TABLE 2.
Ferret mortality following 1918 VLP vaccination and lethal H5N1 challenge
Group | No. of ferrets | No. that survived virus challenge (% mortality) | MTD (days postchallenge) | Serum HI antibody GMT prior to virus challenge
|
|
---|---|---|---|---|---|
1918 | H5N1 | ||||
VLP i.n. | 6 | 6 (0) | NAa | 254 | <20 |
VLP i.m. | 6 | 3 (50) | 8.3 | 180 | <20 |
PBS | 6 | 0 (100) | 6.3 | <20 | <20 |
NA, not applicable.