TABLE 2.
Pathological findings for Cdk2−/− p53−/− mice
| Animal | Sex | Day | Pathological finding(s) for Cdk2−/−p53−/− micea |
|---|---|---|---|
| KM123 | Male | 32 | Skin abscess |
| KM135 | Male | 238 | Lymphoblastic lymphoma, hematopoietic neoplasm, skin sarcoma |
| KM108 | Female | 175 | Lymphoblastic lymphoma |
| KM1139 | Male | 108 | Lymphoblastic lymphoma |
| KM1161 | Male | 113 | Sick, no obvious tumor |
| KM1184 | Male | 66 | Sick, no obvious tumor |
| KM1240 | Female | 62 | Lymphoblastic lymphoma |
| KM1269 | Male | 264 | Lymphoblastic lymphoma |
| KM1304 | Female | 137 | Lymphoblastic lymphoma |
| KM1571 | Female | 98 | Lymphoblastic lymphoma |
| KM1574 | Male | 99 | Lymphoblastic lymphoma, lymphoma in lungs, muscle sarcoma, hematopoietic neoplasm |
| KM1637 | Male | 154 | Lymphoma in lungs, thymic hyperplasia |
| KM1671 | Male | 237 | Lymphoblastic lymphoma, hemangiosarcoma |
| KM1677 | Female | 253 | Granulosa cell tumor |
| KM1697 | Male | 235 | Lymphoma, hematopoietic neoplasm |
| KM1703 | Male | 256 | Skin acanthosis |
| KM1756 | Male | 117 | Lymphoblastic lymphoma, hematopoietic neoplasm |
| KM1793 | Female | 199 | Lymphoblastic lymphoma |
| KM1823 | Male | 185 | Sick, but no obvious tumor |
| KM1843 | Female | 168 | Sick, but no obvious tumor |
| KM1869 | Male | 95 | Lymphoblastic lymphoma |
a
The following animals were found dead (with sex and day of death shown in parentheses): KM1152 (male, day 179), KM1171 (male, day 218), KM1172 (male, day 184), KM1317 (male, day 208), KM1419 (male, day 105), KM1429 (male, day 173), KM1430 (female, day 109), KM1470 (male, 173), and KM1480 (female, day 105).