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Mice generated by Cdk4+/− p53+/− crosses
| Genotype | No. of micea | % of mice
|
|
|---|---|---|---|
| Observed | Expected | ||
| Cdk4+/+p53+/+ | 21 | 9.6 | 6.25 |
| Cdk4+/+p53+/− | 44 | 20.2 | 12.5 |
| Cdk4+/+p53−/− | 9 | 4.1 | 6.25 |
| Cdk4+/−p53+/+ | 38 | 17.4 | 12.5 |
| Cdk4+/−p53+/− | 72 | 33.0 | 25 |
| Cdk4+/−p53−/− | 17 | 7.8 | 12.5 |
| Cdk4−/−p53+/+ | 4* | 1.8 | 6.25 |
| Cdk4−/−p53+/− | 11 | 5.0 | 12.5 |
| Cdk4−/−p53−/− | 2* | 0.9 | 6.25 |
| Total | 218 | ||
*, significant difference from the expected Mendelian ratio.
