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. 2009 Mar 4;83(10):5137–5147. doi: 10.1128/JVI.02179-08

TABLE 1.

Selected proteins that reproducibly increased in the DRM fraction of SGR-N cellsa

Avg ratio P (Student t test) Coverage (%) Protein name Molecular function GI no.
5.56 0.04 27 GRP94 Protein folding 15010550
4.99 0.07 47 Hsp60 Protein folding 6996447
3.73 0.07 6 tRNA guanine transglycosylase Metabolism 30583205
3.56 0.06 23 KIAA0088 Unknown 577295
3.32 0.07 4 Thioredoxin-related protein Unknown 20067392
3.32 0.13 12 Tat binding protein 1 (TBP-1) Cellular processes 20532406
3.06 0.14 22 Aldehyde dehydrogenase 1 Metabolism 2183299
3.06 0.14 14 Chaperonin TRiC/CCT, subunit 2 Protein folding 54696794
2.96 0.04 14 Heat shock 70-kDa protein 4 (HSPA4) Protein folding 6226869
2.96 0.04 29 GRP58 Metabolism/protein folding 2245365
2.94 0.01 37 Mutant β-actin Cytoskeleton organization 28336
2.65 0.17 33 Glutathione S-transferase (GST) Catalytic activity 2204207
2.53 0.04 37 Keratin 19 Cytoskeleton organization 6729681
2.46 0.08 6 Heterogeneous nuclear ribonucleoprotein K Nucleic acid modification 460789
2.45 0.001 13 HMG-coenzyme A synthase Metabolism 30009
2.4 0.02 31 CKB Energy pathway/metabolism 180570
2.4 0.02 11 Cathepsin D Cellular processes 30582659
2.4 0.02 11 C8orf2 Unknown 37181322
2.36 0.1 38 Tropomyosin 4-anaplastic lymphoma kinase fusion protein Cytoskeleton organization 14010354
2.36 0.1 6 Calreticulin Protein folding 30583735
2.33 0.01 29 Quinolinate phosphoribosyltransferase Metabolism 30583301
2.29 0.04 25 Protein disulfide isomerase-related protein 5 Protein folding 1710248
2.29 0.04 16 Tat binding protein 7 (TBP-7) Cellular processes 263099
2.05 0.11 24 Calumenin Metabolism 2809324
2.05 0.12 10 TRiC/CCT, subunit 5 Protein folding 24307939
2.03 0.07 20 Hsp90 beta Protein folding 34304590
2.01 0.07 10 TRiC/CCT, subunit 1 Protein folding 36796
a

The spectra obtained by tandem mass spectrometry were collected using data-dependent mode, and the results were subjected to database (NCBInr) search by Mascot server software (Matrix Science, London, United Kingdom) for peptide assignment. Coverage, the ratio of the portion of protein sequence covered by matched peptides to the whole protein sequence. GI no., GenInfo identifier number.