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. 2009 Mar 11;83(10):5192–5203. doi: 10.1128/JVI.02081-08

TABLE 3.

Cross-protection results after single-dose immunizations and challenge with different H5N1 strains

Immunizationa Protection [no. of survivors/total (%)] against challenge withb:
VN1203 HK156 IN5/05
Inact. whvv 6/6 (100) 6/6 (100) 6/6 (100)
dVV-HA5 6/6 (100) 6/6 (100) 6/6 (100)
rVV-HA5 6/6 (100) 6/6 (100) 6/6 (100)
rVV-HA-VN 6/6 (100) 6/6 (100) 6/6 (100)
VV-Lister 0/6 (0) 0/6 (0) 0/6 (0)
PBS 0/6 (0) 0/6 (0) 0/6 (0)
a

See Table 1 for vaccine abbreviations.

b

Challenge dose, 1 × 105 TCID50; the LD50s for BALB/c mice for the HK156, VN1203, and IN5/05 strains were 11, 24, and 18 TCID50, respectively. Protection of mice was highly significant in the groups immunized with HA-containing vaccines compared to that for the controls (P < 0.001).