Table 5.
Relationship between TAP1 and TAP2 genotypes and oral contraceptive use in women with cervical cancer and healthy controls
| TAP1 | Case (%) | Control (%) | OR(95% CI) | P –valueb |
|---|---|---|---|---|
| TT (none used) | 5 (4.0) | 6 (7.5) | 1.0(ref) | – |
| TT | 5 (6.7) | 1 (0.83) | 1.83(0.87–3.04) | |
| TC | 65 (86.7) | 111 (89.0) | 0.81 (0.41–1.60) | |
| CC | 5 (6.7) | 8 (6.6) | 0.75(0.11–5.13) | |
| TC+CC | 70(35.0) | 119(59.5) | 0.81(0.42–1.60) | |
| TAP2 | ||||
| AA(none used) | 20 (16.0) | 6 (7.5) | 1.0(ref) | – |
| AA | 12 (16.0) | 10 (8.3) | 0.36(0.09–1.46) | |
| AG | 61 (81.3) | 84 (70.0) | 0.55 (0.41–0.73) | P = 0.02 |
| GG | 2 (2.7) | 26 (21.6) | 0.09 (0.02–0.36) | P < 0.001 |
| AA+GG | 63(31.5) | 110(55.5) | 0.47(0.35–0.63) | 0.0002 |
Abbreviations: CI confidence interval, OR odds ratio, ref Reference
aORs were adjusted for age and smoking status
bp < 0.05 has been mentioned