Table 2.

Multivariable-adjusted^* hazard ratios (HRs) and 95% confidence intervals (CIs) for ischemic vascular events according to single nucleotide polymorphisms Gly16Arg, Gln27Glu, and Thr164Ile in the ADRB2 gene among women in the Women’ Health Study (n=25,224) assuming an additive mode

Polymorphisms	HR	95% CI	p-value
Myocardial infarction (n=274)
Gly16Arg	1.06	0.89−1.27	0.50
Gln27Glu	1.08	0.91−1.28	0.39
Thr164Ile	0.92	0.44−1.92	0.83
Ischemic stroke (n=299)
Gly16Arg	1.07	0.90−1.26	0.46
Gln27Glu	0.85	0.72−1.00	0.06
Thr164Ile	1.03	0.54−1.96	0.92
Death due to cardiovascular disease (n=159)
Gly16Arg	0.93	0.74−1.18	0.55
Gln27Glu	1.02	0.82−1.28	0.86
Thr164Ile	1.11	0.47−2.62	0.82

^*adjusting for: age, body mass index, history of hypertension, diabetes, physical activity, smoking categories, alcohol consumption, postmenopausal hormone use, oral contraceptive use, family history of myocardial infarction before age 60, and randomized aspirin assignment.