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Overall 5-year survival curve of colorectal adenocarcinoma patients with TSPAN1 negative (-) and TSPAN1 positive (+, ++, +++) for the entire cohort (P = 0.001) was estimated by Kaplan-Meier test. Survival rate in TSPAN1 expression groups (++, +++) were obviously lower than that of weak expression (+) or negative (-) group, respectively (P < 0.05). There was no significant difference of survival rates between TSPAN1 negative group (-) and TSPAN1 weak expression group (+).
