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. 2008 Nov 3;328(2):469–477. doi: 10.1124/jpet.108.145409

Fig. 6.

Fig. 6.

Expression of genes involved in cell proliferation, tumor suppression, and inflammation in the colons of 2- and 12-month-old male WT and FXR KO mice. A, mRNA levels of genes in 2-month-old male mice. B, mRNA levels of genes in 12-month-old male mice. n = 6/genotype/time point. *, P < 0.05. C, Western blot analysis of cyclin D1, c-Myc, β-catenin, and APC protein in the colon of 2- and 12-month-old WT and FXR KO male mice, with n = 6 per group. D, immunohistochemistry staining of β-catenin in the colon of 2- and 12-month-old WT and FXR KO male mice.