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Sedative effects of intravenous salvinorin A (0.032 and 0.1 mg/kg) in chaired subjects (n = 3; dose ranging study) (left). Sedative effects of U69,593 (0.01, 0.032, and 0.056 mg/kg i.v.) (right). Abscissae, time from intravenous injection (minutes); ordinates, median sedation score. Points above “BL” represent median baseline preinjection values.
