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Comparison of effects of drugs on recombinant and native nAChRs. Linear regression analysis of IC50 values of all our drugs on nicotine-stimulated calcium accumulation (recombinant nAChRs) and adrenal neurosecretion (native nAChRs) was performed. Actual IC50 values for recombinant nAChRs are found in Table 1. Values for native nAChRs are from McKay et al. (2007) and Bergmeier et al. (2004).
