Fig. 9.

Effects of APB-8 on [³H]epibatidine binding. [³H]epibatidine homologous competition binding experiments were performed on adrenal medulla membranes in the absence (•) and presence of 10 μM APB-8 (○). Data are expressed as percentage specific [³H]epibatidine binding or as specific [³H]epibatidine binding in femtomoles per milligram of protein (inset). Triangles represent [³H]epibatidine binding in the absence of epibatidine (inset). Values represent means ± S.E.M. (n = 4).