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A. Behavioral changes after the pallidal lesions and GDNF reinstatement. A transient behavioral improvement was observed after the pallidal lesioning and faded away 3 months post-surgery. The GDNF reinstatement did not induce any behavioral changes in any lesioned animal. B. Behavioral improvements were found immediately after the reinstatement of GDNF in animals without any pallidal lesion and were sustained throughout the study.
