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. Author manuscript; available in PMC: 2009 May 14.
Published in final edited form as: Biochim Biophys Acta. 2007 Jul 6;1769(9-10):546–558. doi: 10.1016/j.bbaexp.2007.06.004

FIGURE 1.

FIGURE 1

(A) The human ITGA1-PELO-ITGA2 locus is situated on chromosome 5q11.2 ITGA1 is separated from ITGA2 by only 32 Kb. The locus is demarcated by the expressed sequence tag (EST) D5S202 at the 5′ end, D5S623 in the center and D5S2037 at the 3′ end. (B) The human PELO gene is embedded within intron 1 of ITGA1. Human PELO consists of two translated exons (Exons 2 and 3) that encode the 385 amino acid protein, pelota. An untranslated Exon 1 starts 11.1kb downstream from the beginning of ITGA1 intron 1.