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Hyaluronic acid (HA) fillers: crosslinking agents and concentration of HA
| Product | Captique | Hylaform | Juvéderm Ultra and Ultra Plus | Puragen | Prevelle | Restylane and Perlane |
|---|---|---|---|---|---|---|
| Crosslinking agent | DVS | DVS | BDDE | DEO | DVS | BDDE |
| Concentration | 4.5–6.5 mg/mL | 4.5–6.5 mg/mL | 24 mg/mL | 20 mg/mL | 4.5–6.5 mg/mL | 20 mg/mL |
Abbreviations: BDDE, 1,4-butanediol diglycidyl ether; DVS, divinyl sulphone; DEO, 2, 7, 8-diepoxyoctane.
