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. 2008 Nov 12;4(5):458–469. doi: 10.1016/j.chom.2008.10.003

Figure 3.

Figure 3

Atg5 Is Not Globally Required for IFN-γ-Induction of Transcription or NO Production

(A) Shown is the induction of expression of the indicated genes as measured by qRT-PCR at 16 hr after treatment of control, or Atg5-deficient macrophages with LPS, IFN-γ, or the combination of IFN-γ/LPS. Data were pooled from two independent experiments and presented as mean ± SEM. There were no statistically significant differences between control and Atg5-deficient macrophages.

(B) Shown are the levels of NO produced by macrophages stimulated by IFN-γ/LPS for 18 hr. DPI is an inhibitor of NO production. Data were pooled from two independent experiments and presented as mean ± SEM.