Figure 1.

Genomic structure, relative single nucleotide polymorphism (SNP) positions, and linkage disequilibrium (LD) plots for the six genes showing evidence for association. The SNP haplotype windows with global p values ≤ .01 are indicated above the genomic structure of the gene. The shown haplotype-based p value for EPB41L4A is from an analysis of two non-adjacent SNPs. The rs-numbers of SNPs showing p ≤ .01 in the single-point analysis are highlighted in green. The triangular plots represent pairwise comparisons of intermarker LD, measured in D'. The span of the coding sequence of each gene is depicted with a green line. Figure modified from Locusview2.0 output (T. Petryshen, A. Kirby, and M. Ainscow, unpublished software).