Table 2.
Six locus haplotypes in the PKLR region
| SNP | RS3180018 | RS6836863 | RS8847 | RS1052177 | RS11264359 | RS11264351 | Frequency |
|---|---|---|---|---|---|---|---|
| Location | 153,496,775 | 153,507,985 | 153,525,947 | 153,526,974 | 153,549,453 | 153,556,169 | |
| 1 | C | G | G | T | T | A | 0.71 |
| 2 | T | A | A | C | G | G | 0.24 |
| 2a | C | A | A | C | G | G | 0.01 |
| 2b | T | A | A | C | T | A | 0.01 |
Shown are four observed haplotypes with over 1% allele frequency estimated using the expectation maximization algorithm in HaploView 4.1. Locations of the six tag SNPs are given in base pairs based on build 35. For purposes of this study, haplotypes 2, 2a, and 2b were considered the same. Recombinant bases are marked in bold.