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Degradation and cell association of HDL are reduced in murine RAW macrophages stably expressing the SR-BI G2S variant. A, Degradation of [125I, 3H]-labeled HDL was significantly lower in G2S expressing cells (P < 0.0004). B, Specific 125I and [3H]CE cell association (panel C) were significantly lower in G2S expressing cells (*, P < 0.0004 compared to wild-type).
