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. Author manuscript; available in PMC: 2010 Jan 1.
Published in final edited form as: Dev Dyn. 2009 Jan;238(1):76–85. doi: 10.1002/dvdy.21815

Figure 2. Heterozygous fish from the tumor-prone hi258 (rpL35) line are growth-impaired.

Figure 2

(A) The offspring of an outcross of a hi258 (rpL35) heterozygote, expected to be 50% hi258 heterozygous and 50% wild-type, are widely variable in size at 28 days of age. The fish were housed in a single tank.

(B) hi258 heterozygotes (HET) are generally smaller than their wild-type siblings (WT). Representative fish from the group depicted in (A) are shown with their weights and genotype. Scale bar in each image is 5 mm. The weights of all fish in (A) are listed in Table S2.

(C) hi258 heterozygotes were outcrossed to T-AB wild-type fish, and their progeny were housed in the same tank. At selected time points, fish were weighed and genotyped. hi258 heterozygotes are significantly smaller than their wild-type siblings at every age examined. Error bars are ±2 SEM.