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Grade 3 and 4 toxicity during a total of 34 cycles of ICE
| Toxicity | No. courses with toxicity (%) |
|---|---|
| Absolute neutrophil count <1,000/μl | 25 (74%) |
| WBC Count <2,000/μl | 24 (71%) |
| Hemoglobin <8 g/dl | 23 (68%) |
| Platelet count <50,000/μl | 23 (68%) |
| RBC transfusion(s) | 31 (91%) |
| Platelet transfusion(s) | 19 (56%) |
| Grade 3 nausea | 3 (9%) |
| Fever in absence of infection | 2 (6%) |
| Grade 3 allergy to etoposide | 1 (3%) |
