Table 2. Hemagglutination Inhibition (HI) titers of the mAbs against H5N1 influenza viruses.
H5N1 strain | Clade | HI titers of the mAbs | ||
2D9a | 4C2a | 2D9+4C2b | ||
A/Hongkong/156/97 | 0 | 128 | 256 | 256 |
A/HongKong/213/03 | 1 | 512 | 256 | 512 |
A/Vietnam/1203/04 | 1 | 512 | 512 | 512 |
A/Indonesia/TLL014/06 | 2.1 | 128 | 256 | 256 |
A/Indonesia/CDC540/06 | 2.1 | 256 | <8 | 128 |
A/Indonesia/CDC669/06 | 2.1 | 512 | 256 | 512 |
A/Indonesia/CDC1031/07 | 2.1 | 256 | 512 | 512 |
A/turkey/Turkey1/05 | 2.2 | 256 | 128 | 256 |
A/barheaded goose/Qinghai/12/05 | 2.2 | 256 | 128 | 256 |
A/Nigeria/6e/07 | 2.2 | 128 | 64 | 128 |
A/Egypt/0636-NAMRU3/07 | 2.2 | 64 | 256 | 128 |
A/Anhui/1/05 | 2.3 | 512 | 256 | 512 |
A/chicken/Nongkhai/NIAH400802/07 | 2.3 | 256 | 128 | 256 |
A/VietNam/HN31242/07 | 2.3 | 512 | 128 | 256 |
A/goose/Guiyang/337/06 | 4 | 128 | 256 | 256 |
A/chicken/Shanxi/2/06 | 7 | 256 | 64 | 128 |
A/chicken/Henan/12/04 | 8 | 256 | 256 | 512 |
EM* 2D9 mAb A/Indonesia/CDC669/06 | <8 | 256 | 128 | |
EM* 4C2 mAb A/Indonesia/CDC669/06 | 512 | <8 | 256 |
Concentration of mAb at 500 µg/ml.
Concentration of each mAb at 250 µg/ml.
EM indicates Escape Mutant against the mAb mentioned.