Table 2. Do thiazides diuretics have a significant effect on blood pressure variability?
Review 1 | Thiazide group | Placebo group |
SD of SBP±SE mmHg | ||
Baseline | 14.9±0.99 (n = 14)∧ | 14.1±0.75 (n = 14)∧ |
End of treatment ∧∧ | 14.3±0.71 (n = 14) | 14.0±0.82 (n = 14) |
CV of SBP±SE % | ||
Baseline | 9.5±0.57 (n = 14)∧ | 9.0±0.39 (n = 14)∧ |
End of treatment ∧∧ | 9.9±0.42 (n = 14) | 9.4±0.53 (n = 14) |
SD of DBP±SE * mmHg | ||
End of treatment ∧∧ | 7.6±0.37 (n = 23) | 6.9±0.39 (n = 23) |
CV of DBP±SE * % | ||
End of treatment ∧∧ | 8.2±0.39 (n = 23) | 7.2±0.43 (n = 23) |
SD = Standard Deviation; SE = Standard Error; SBP = Systolic Blood Pressure; DBP = Diastolic Blood Pressure; CV = Coefficient of Variation; n = number of observations.
Paired t test between baseline versus end of treatment is not significant for SD of SBP as well as CV of SBP in both thiazide and placebo groups.
Only end of treatment values for SD as well as CV of DBP were analyzed since baseline values are confounded.
Unpaired t test at end of treatment between thiazide versus placebo groups is not significant for SD as well as CV of both SBP and DBP.