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. 2009 May 22;4(5):e5673. doi: 10.1371/journal.pone.0005673

Table 2. Do thiazides diuretics have a significant effect on blood pressure variability?

Review 1 Thiazide group Placebo group
SD of SBP±SE mmHg
Baseline 14.9±0.99 (n = 14) 14.1±0.75 (n = 14)
End of treatment ∧∧ 14.3±0.71 (n = 14) 14.0±0.82 (n = 14)
CV of SBP±SE %
Baseline 9.5±0.57 (n = 14) 9.0±0.39 (n = 14)
End of treatment ∧∧ 9.9±0.42 (n = 14) 9.4±0.53 (n = 14)
SD of DBP±SE * mmHg
End of treatment ∧∧ 7.6±0.37 (n = 23) 6.9±0.39 (n = 23)
CV of DBP±SE * %
End of treatment ∧∧ 8.2±0.39 (n = 23) 7.2±0.43 (n = 23)

SD = Standard Deviation; SE = Standard Error; SBP = Systolic Blood Pressure; DBP = Diastolic Blood Pressure; CV = Coefficient of Variation; n = number of observations.

Paired t test between baseline versus end of treatment is not significant for SD of SBP as well as CV of SBP in both thiazide and placebo groups.

*

Only end of treatment values for SD as well as CV of DBP were analyzed since baseline values are confounded.

∧∧

Unpaired t test at end of treatment between thiazide versus placebo groups is not significant for SD as well as CV of both SBP and DBP.