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. 2009 Apr 15;328(2):285–296. doi: 10.1016/j.ydbio.2009.01.030

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© 2009 Elsevier Inc.

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Fig. 3 — Mice homozygous for the catweasel have middle and inner ear defects. (A–C) Dissected middle ear ossicles from wildtype (A), Cwe/+ (B) and Cwe/Cwe (C) animals. The long process of the incus was absent in Cwe/Cwe mice (arrowhead). (D–F) Analysis of gross morphology of the inner ear of wildtype (A), Cwe/+ (B) and Cwe/Cwe (C) mice at P21 by glycerol clearing. (G–I) Analysis of gross morphology of the inner ear of wildtype (D), Cwe/+ (E) and Cwe/Cwe (F) embryos at E18.5 by paintfilling. Scale bars: A–C = 500 μm, D–F = 1 mm, G–I = 300 μm; m, malleus; i, incus; lp, long process incus; s, stapes; aa, anterior ampulla; ac, anterior semicircular canal; cc, common crus; co, cochlea; la, lateral ampulla; lc, lateral semicircular canal; pa, posterior ampulla; pc, posterior semicircular canal; sa, saccule.