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. 2009 May 27;4(5):e5697. doi: 10.1371/journal.pone.0005697

Figure 2. Ethanol-induced phosphorylation of synapsin I and II and eEF-2 is compromised in DKO hippocampus.

Figure 2

(A) Immunoblot analysis of whole cell lysates from WT and DKO mice demonstrates increased expression of phosphorylated synapsin I and II (psyn I, II) and eEF-2 (peEF-2) in WT, but not DKO hippocampus following ethanol treatment compared to saline controls. (B) Quantification of phospho-synapsin I, II and phospho-eEF-2 expression normalized to total synapsin I, II (syn I, II) or eEF-2 expression, respectively. Ethanol significantly induced phosphorylation of synapsin I, II and eEF-2 in WT, but not DKO mice. (**, p<0.05 vs. WT saline).