TABLE 1.
Baseline clinical and laboratory characteristics of control subjects and first-degree relatives of type 2 diabetic patients and relative subgroups: RESP and NRES of ATP-synthesis to exercise training
| Control | Relatives | RESP | NRES | |
|---|---|---|---|---|
| n(women/men) | 12 (6/6) | 24 (13/11) | 10 (4/6) | 14 (9/5) |
| Age (years) | 37 ± 11 (30–44) | 40 ± 12 (35–45) | 41 ± 15 (31–52) | 39 ± 11 (33–46) |
| Body weight (kg) | 71 ± 13 (63–79) | 73 ± 14 (68–79) | 76 ± 14 (65–86) | 72 ± 13 (64–79) |
| BMI (kg/m2) | 23 ± 2 (22–25) | 25 ± 4 (24–27) | 26 ± 4 (23–29) | 25 ± 4 (22–27) |
| Waist-to-hip ratio | 0.83 ± 0.08 (0.78–0.88) | 0.85 ± 0.05 (0.83–0.87) | 0.87 ± 0.04 (0.84–0.90) | 0.84 ± 0.05 (0.81–0.87) |
| Systolic blood pressure (mmHg) | 124 ± 19 (112–135) | 126 ± 11 (121–130) | 127 ± 11 (119–135) | 125 ± 12 (118–132) |
| Diastolic blood pressure (mmHg) | 82 ± 10 (76–88) | 83 ± 8 (79–86) | 82 ± 8 (76–88) | 84 ± 8 (79–88) |
| A1C (%) | 5.3 ± 0.3 (5.1–5.5) | 5.4 ± 0.3 (5.3–5.6) | 5.5 ± 0.4 (5.2–5.7) | 5.4 ± 0.3 (5.3–5.6) |
| Triglycerides (mmol/l) | 0.87 ± 0.50 (0.53–1.20) | 1.23 ± 0.70 (0.94–1.53) | 1.32 ± 0.57 (0.91–1.73) | 1.18 ± 0.80 (0.72–1.64) |
| HDL cholesterol (mmol/l) | 1.7 ± 0.45 (1.4–2.0) | 1.5 ± 0.4 (1.3–1.6) | 1.4 ± 0.4 (1.1–1.7) | 1.5 ± 0.4 (1.3–1.7) |
| LDL cholesterol (mmol/l) | 3.0 ± 0.7 (2.5–3.4) | 3.5 ± 0.9 (3.1–3.9) | 3.8 ± 0.9 (3.2–4.4) | 3.3 ± 1.0 (2.8–3.9) |
| Physical activity (scale 1–5) | 2.7 ± 0.3 (2.5–2.9) | 2.9 ± 0.3 (2.7–3.0) | 2.9 ± 0.3 (2.6–3.1) | 2.9 ± 0.3 (2.7–3.1) |
| VO2max(ml · kg−1· min−1) | 33.6 ± 6.0 (29.8–37.5) | 30.6 ± 6.4 (27.8–33.3) | 29.6 ± 5.5 (25.7–33.6) | 31.2 ± 7.1 (27.1–35.3) |
| VO2RCP(ml · kg−1· min−1) | 26.2 ± 4.8 (23.1–29.2) | 22.8 ± 5.7 (20.4–25.2) | 22.1 ± 4.7 (18.7–25.4) | 23.3 ± 6.4 (19.6–27.0) |
Data are means ± SD (95% CI). NRES, not responding to exercise with stimulation of fATPase; RESP, responding to stimulation of fATPase.