TABLE 4.
Association between SNPs in the NDUFB6(rs540467) and PPARGC1A(rs8192678,Gly482Ser) genes and response to exercise training regarding stimulation of fATPase and dynamic insulin sensitivity (OGIS) in RESP and NRES
| G/G | G/A | A/A | P values | |
|---|---|---|---|---|
| NDUFB6 rs540467 | ||||
| fATPase | ||||
| RESP | 14 | 4 | 1 | 0.02* |
| NRES | 5 | 9 | 1 | |
| OGIS | ||||
| RESP | 16 | 7 | 1 | 0.05* |
| NRES | 3 | 6 | 1 |
| Gly/Gly | Gly/Ser | Ser/Ser | P values | |
|---|---|---|---|---|
| PPARGC1A rs8192678 | ||||
| fATPase | ||||
| RESP | 9 | 10 | 0 | 0.24 |
| NRES | 7 | 6 | 2 | |
| OGIS | ||||
| RESP | 11 | 11 | 2 | 0.64 |
| NRES | 5 | 5 | 0 |
χ2tests were performed to analyze associations between genotypes and response to exercise for fATPase and OGIS.
*P value indicating significance for a dominant model. NRES, not responding to exercise with stimulation of fATPase; RESP, responding to exercise with stimulation of fATPase.