TABLE 2.

Numbers of total and Ki-67–positive nuclei in islets

	Counted islets per animal	Counted nuclei per animal	Nuclei per islet	Proportion of Ki-67–positive nuclei per islet (%)
Wild type	68	6,297 ± 664.5	93 ± 7.6	1.10 ± 0.08
Transgenic	60	5,291 ± 567.7	89 ± 9.7	1.16 ± 0.13

Data are means ± SE of values from four animals from each genotype. Pancreatic sections were immunostained with the anti–Ki-67 antibody followed by counterstaining with hematoxylin as shown inFig. 3I. Numbers of all nuclei and of Ki-67–positive nuclei in the islets of wild-type and transgenic mice were counted.