Table 1.
Likely candidates for phase I trials of CBI-NCs
| Company | Location | Target condition | Current cell types | Link |
|---|---|---|---|---|
| Athersys Inc. | Ohio (USA) | Stroke | MultiStem™ platform based on the multipotent adult progenitor cell (MAPC) technology | http://www.athersys.com/Home/ProductCandidates/MultiStemforStroke/tabid/75/Default.aspx |
| BrainStorm Cell Therapeutics | Israel | Parkinson’s disease | Human embryonic stem cells and adult stem cells, sourced from bone marrow, cord blood, and various organs | http://www.brainstorm-cell.com/Index.asp?ArticleID = 153&CategoryID = 76&Page = 2 |
| California Stem Cell | California (USA) | ALS, SMA, spinal cord injury | Human embryonic stem cells | http://www.californiastemcell.com/press/release/pr_1203425660 |
| Geron | California (USA) | Spinal cord injury | Human embryonic stem cells | http://www.geron.com/media/pressview.aspx?id = 840 |
| Living Cell Technologies Ltd | Australia, New Zealand, Italy, Rhode Island (USA) | Huntington’s disease, Parkinson’s disease, Stroke | Porcine choroid plexus brain cells encased in a biopolymer capsule developed from seaweed | http://www.lct.com.au/lctneurotrophincell-parkinsonstreatment.php |
| ReNeuron | United Kingdom | Stroke | Stem cells derived from fetal human somatic tissue | http://www.reneuron.com/programmes/stroke/ |
| Stem Cells Inc. | California (USA) | Batten’s disease | Stem cells harvested from fetal human brain tissue | http://www.stemcellsinc.com/news/080118.html, see also http://www.clinicaltrials.gov/ct2/show/NCT00337636 |
CNS, central nervous system; PD, Parkinson’s disease.