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. Author manuscript; available in PMC: 2010 Apr 1.
Published in final edited form as: Stroke. 2009 Feb 20;40(4):1044–1049. doi: 10.1161/STROKEAHA.108.542993

Table 3.

Associations of bone mineral density measured at three sites and risk of incident ischemic stroke among women in the Framingham Heart Study (n=654).

Quintile of BMD Number of Participants Number of Ischemic Strokes Age-adjusted Multivariable-adjusted*
HR 95% CI P HR 95% CI P
Femoral neck
Q1 122 18 1.37 0.69-2.73 0.36 1.33 0.66-2.68 0.42
Q2 124 18 1.25 0.63-2.38 0.53 1.30 0.65-2.59 0.45
Q3 126 15 1.00 1.00
Q4 124 17 1.18 0.59-2.36 0.65 0.92 0.45-1.88 0.81
Q5 124 24 1.72 0.90-3.29 0.10 1.41 0.72-2.76 0.32
Trochanter
Q1 125 25 2.17 1.07-4.38 0.03 2.36 1.15-4.83 0.02
Q2 127 19 1.13 0.51-2.52 0.76 1.07 0.48-2.41 0.87
Q3 128 9 1.00 1.00
Q4 131 18 1.90 0.93-3.86 0.08 1.77 0.86-3.64 0.12
Q5 126 24 2.38 1.19-4.77 0.01 1.94 0.94-3.95 0.07
Radius
Q1 122 22 3.18 1.48-6.82 0.00 2.92 1.55-6.34 0.01
Q2 123 12 2.10 0.95-4.65 0.07 1.94 0.87-4.32 0.11
Q3 125 12 1.00 1.00
Q4 123 21 2.07 0.93-4.60 0.08 1.68 0.74-3.80 0.21
Q5 123 24 2.92 1.36-6.28 0.01 2.43 1.12-5.30 0.03

Q = quintile, HR = hazard ratio, CI = confidence interval, BMD = bone mineral density

*

Adjusted for age, systolic blood pressure, atrial fibrillation, diabetes, current smoking, cardiovascular disease, estrogen use, and body mass index.

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